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  <front>
    <journal-meta>
      <journal-id journal-id-type="issn">2542-1298</journal-id>
      <journal-id journal-id-type="eissn">2687-1491</journal-id>
      <journal-title-group>
        <journal-title xml:lang="ru">Журнал медико-биологических исследований</journal-title>
        <journal-title xml:lang="en">Journal of Medical and Biological Research</journal-title>
      </journal-title-group>
      <publisher>
        <publisher-name>Северный (Арктический) федеральный университет</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.37482/2687-1491-Z273</article-id>
      <article-id pub-id-type="uri">https://journals.narfu.ru/index.php/med/article/view/1909</article-id>
      <title-group>
        <article-title xml:lang="ru">Динамика показателей внешнего дыхания у молодых женщин в ходе менструального цикла</article-title>
        <trans-title-group xml:lang="en">
          <trans-title>Dynamics of Respiratory Parameters in Young Women During the Menstrual Cycle</trans-title>
        </trans-title-group>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name name-style="eastern">
            <surname>Сапёрова</surname>
            <given-names>Елена Владимировна</given-names>
          </name>
          <name-alternatives>
            <name name-style="eastern" xml:lang="ru">
              <surname>Сапёрова</surname>
              <given-names>Елена Владимировна</given-names>
            </name>
            <name name-style="western" xml:lang="en">
              <surname>Saperova</surname>
              <given-names>Elena V.</given-names>
            </name>
          </name-alternatives>
          <email>saperova_elena@mail.ru</email>
          <contrib-id contrib-id-type="orcid">0000-0001-5335-3238</contrib-id>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <aff-alternatives id="aff1">
          <aff>
            <institution xml:lang="ru">Чувашский государственный педагогический университет им. И.Я. Яковлева (Чебоксары, Россия)</institution>
          </aff>
          <aff>
            <institution xml:lang="en">Chuvash I. Yakovlev State Pedagogical University (Cheboksary, Russia)</institution>
          </aff>
        </aff-alternatives>
      </contrib-group>
      <pub-date pub-type="epub" iso-8601-date="2026-03-11">
        <day>11</day>
        <month>03</month>
        <year>2026</year>
      </pub-date>
      <volume>14</volume>
      <issue>1</issue>
      <fpage>43</fpage>
      <lpage>51</lpage>
      <history>
        <date date-type="received" iso-8601-date="2025-05-08">
          <day>08</day>
          <month>05</month>
          <year>2025</year>
        </date>
        <date date-type="accepted" iso-8601-date="2025-11-27">
          <day>27</day>
          <month>11</month>
          <year>2025</year>
        </date>
        <date date-type="rev-recd" iso-8601-date="2025-11-24">
          <day>24</day>
          <month>11</month>
          <year>2025</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>Сапёрова Е.В., 2026</copyright-statement>
        <copyright-year>2026</copyright-year>
        <copyright-holder xml:lang="ru">Сапёрова Е.В.</copyright-holder>
        <copyright-holder xml:lang="en">Saperova E.V.</copyright-holder>
        <license xlink:href="https://creativecommons.org/licenses/by/4.0/">
          <license-p>CC BY 4.0</license-p>
        </license>
      </permissions>
      <self-uri xlink:type="simple" xlink:href="https://journals.narfu.ru/index.php/med/article/view/1909">https://journals.narfu.ru/index.php/med/article/view/1909</self-uri>
      <abstract xml:lang="ru">
        <p>Менструальный цикл является естественным физиологическим процессом женщин. Изменения уровня гормонов в их организме в разные фазы цикла играют роль в функционировании дыхательной системы, однако литературные данные указывают на недостаточную изученность данного вопроса. Цель работы – сравнение параметров внешнего дыхания у молодых женщин в разные фазы менструального цикла. Материалы и методы. У 15 женщин 20–25 лет ежедневно в течение двух последовательных менструальных циклов измеряли показатели внешнего дыхания посредством компьютерного спирометра «Спиро-Спектр» («Нейрософт», Россия). Результаты. Максимальные значения частоты дыхания (ЧД) и дыхательного объема (ДО) наблюдались в лютеиновую фазу (ЛФ) цикла (р &lt; 0,01). Минутный объем дыхания, являющийся производным показателем от ЧД и ДО, имел максимум в середине ЛФ и минимум в конце фолликулиновой фазы (ФФ) (р &lt; 0,01). Наибольшие значения жизненной емкости легких и форсированной жизненной емкости легких были характерны для начала ЛФ, минимальные – для середины ФФ (р &lt; 0,01 и р &lt; 0,05 соответственно). Анализ изменения пиковой объемной скорости, отражающей проводимость бронхов, свидетельствует о повышении данного показателя к началу ЛФ с минимумом в конце ФФ (р &lt; 0,01). Аналогичная картина имела место и для других параметров проводимости бронхов: объема форсированного выдоха за первую секунду и индекса Тиффно. Значение максимальной вентиляции легких (МВЛ) было выше в ЛФ цикла (р &lt; 0,05). ЧД при выполнении теста на МВЛ была минимальной в конце ФФ и увеличилась к началу ЛФ (р &lt; 0,01). Анализ проводимости бронхов разных диаметров позволил выявить достоверное изменение лишь для крупных бронхов в раннюю ЛФ. Таким образом, исследование обнаружило достоверные изменения как статических, так и динамических показателей внешнего дыхания молодых женщин в течение менструального цикла.</p>
      </abstract>
      <trans-abstract xml:lang="en">
        <p>The menstrual cycle is a natural physiological process in women. Changes in hormone levels in their bodies during different phases of the cycle affect the respiratory system. However, literature data indicate that this issue has not been sufficiently studied. The purpose of this article was to investigate the dynamics of respiratory parameters during different phases of the menstrual cycle. Methods. Respiratory parameters were measured daily for two consecutive menstrual cycles in 15 women aged 20–25 years using a computer-based spirometer Spiro-Spectrum (Neurosoft, Russia). Results. Maximal values of the respiratory rate (RR) and tidal volume (TV) were observed in the luteal phase (LP) of the menstrual cycle (p &lt; 0.01). Minute volume, which is derived from RR and TV, reached a maximum in the middle of LF and a minimum at the end of the follicular phase (FP) (p &lt; 0.01). The highest values of vital capacity (VC) and forced VC were observed at the beginning of LP, while the lowest, in the middle of FP (p &lt; 0.01 and p &lt; 0.05, respectively). The analysis of changes in peak expiratory flow, reflecting bronchial conduction, showed that this parameter increased by the beginning of LP and reached a minimum at the end of FP (p &lt; 0.01). A similar pattern was observed with other parameters reflecting bronchial conduction: forced expiratory volume in the 1st second (FEV1) and the FEV1/VC ratio. The value of maximal voluntary ventilation (MVV) was higher in the LP (p &lt; 0.05). During the MVV test, RR was minimal at the end of FP and increased by the beginning of LP (p &lt; 0.01). The study of the conductivity of bronchi of different diameters found a significant change in the conductivity of only large-diameter bronchi in the early LP. Thus, the research established significant changes in both static and dynamic parameters of external respiration in young women in the course of the menstrual cycle.</p>
      </trans-abstract>
      <kwd-group xml:lang="ru">
        <title>Ключевые слова</title>
        <kwd>менструальный цикл</kwd>
        <kwd>лютеиновая фаза</kwd>
        <kwd>фолликулиновая фаза</kwd>
        <kwd>показатели внешнего дыхания</kwd>
        <kwd>частота дыхания</kwd>
        <kwd>жизненная емкость легких</kwd>
      </kwd-group>
      <kwd-group xml:lang="en">
        <title>Keywords</title>
        <kwd>menstrual cycle</kwd>
        <kwd>luteal phase</kwd>
        <kwd>follicular phase</kwd>
        <kwd>respiratory parameters</kwd>
        <kwd>respiratory rate</kwd>
        <kwd>vital capacity</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body/>
  <back>
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        <mixed-citation xml:lang="en">15. Prarthana K.G., Suja P., Nayanatara A.K., Adarsh S., Chaitra U. Association of Serum Progesterone Level, Peak Expiratory Flow Rate and Obesity in Healthy Young Women. Clin. ter., 2024, vol. 175, no. 5, pp. 287–290. https://doi.org/10.7417/ct.2024.5132</mixed-citation>
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        <mixed-citation xml:lang="en">16. LoMauro A., Aliverti A. Sex and Gender in Respiratory Physiology. Eur. Respir. Rev., 2021, vol. 30, no. 162. Art. no. 210038. https://doi.org/10.1183/16000617.0038-2021</mixed-citation>
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        <mixed-citation xml:lang="en">18. Resmi S.S., Samuel E., Kesavachandran C., Shashidhar S. Effect of Oral Contraceptives on Respiratory Function. Indian J. Physiol. Pharmacol., 2002, vol. 46, no. 3, pp. 361–366.</mixed-citation>
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