ECG Amplitude Parameters in Men of Different Ages During Submaximal Performance Testing (Exemplified by Residents of the European North of Russia)

Authors

DOI:

https://doi.org/10.37482/2687-1491-Z146

Keywords:

males, European North of Russia, age-related changes, ECG amplitude parameters, PWC170 test, physical work capacity

Abstract

The purpose of this study was to investigate the effect of submaximal physical activity (PWC170 test) on electrocardiogram (ECG) amplitude parameters in men of different ages. Materials and methods. The research involved apparently healthy men aged 20–29 (n = 27) and 40–49 (n = 27) years living in the European North of Russia. They performed a bicycle ergometer PWC170 test with incrementally increasing 3-minute loads (50, 100 and 150 W) and ECG recording in the Nehb leads. Results. A and D leads showed the most informative dynamics of ECG parameters in the subjects during the exercise test. It was mainly expressed in an increase in P wave amplitude, a decrease in T wave amplitude, a deepening of the S wave, and ST segment depression. The group of 40–49-year-old men, compared to 20–29-year-olds, was characterized by less pronounced T wave (lead D) amplitude changes at the beginning of the test, a less deep S wave (lead I), no shift in the ST segment (lead D) as well as a smaller number of parameters that showed statistically significant changes in the exercise test. ST segment (lead A) depression during the final load was twice as common in the older group of men (13 % in 20–29-year-olds and 25 % in 40–49-year-olds). Heart rate (HR) at all stages of the test, except for the last one, was lower in 40–49-year-olds; however, its more significant increase by the end of the test eliminated the statistical differences in HR at the final stage and in physical work capacity (PWC170) between the groups. The revealed differences in ECG and HR parameters may be associated with morphological changes occurring in the cardiovascular system with age, in particular, with the decrease in left ventricular function. Submaximal physical activity in men of the older age group involves a greater expenditure of myocardial reserves.

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References

Smarż K., Jaxa-Chamiec T., Bednarczyk T., Bednarz B., Eysymontt Z., Gałaszek M., Jegier A., KorzeniowskaKubacka I., Mamcarz A., Mawlichanów A., Piotrowicz R., Rubicki J., Straburzyńska-Migaj E., Szalewska D., Wolszakiewicz J. Electrocardiographic Exercise Testing in Adults: Performance and Interpretation. An Expert Opinion of the Polish Cardiac Society Working Group on Cardiac Rehabilitation and Exercise Physiology // Kardiol. Pol. 2019. Vol. 77, № 3. Р. 399–408. DOI: 10.5603/KP.a2018.0241

Pelliccia A., Sharma S., Gati S., Bäck M., Börjesson M., Caselli S., Collet J.P., Corrado D., Drezner J.A., Halle M., et al. 2020 ESC Guidelines on Sports Cardiology and Exercise in Patients with Cardiovascular Disease // Eur. Heart J. 2021. Vol. 42, № 1. Р. 17–96. DOI: 10.1093/eurheartj/ehaa605

Карпман В.Л., Белоцерковский З.Б., Гудков И.А. Исследование физической работоспособности у спортсменов. М.: Физкультура и спорт, 1974. 95 с.

Завьялов А.И. Классификация изменений электрокардиограммы у здорового человека в покое и во время физических нагрузок // Вестн. Краснояр. гос. пед. ун-та им. В.П. Астафьева. 2013. № 4(26). C. 147–151.

Ванюшин Ю.С., Хайруллин Р.Р. Кардиореспираторная система как индикатор функционального состояния организма спортсменов // Теория и практика физ. культуры. 2015. № 7. С. 11–14.

Фудин Н.А., Классина С.Я., Пигарева С.Н. Взаимосвязь показателей мышечной и сердечно-сосудистой систем при возрастающей физической нагрузке у лиц, занимающихся физической культурой и спортом // Физиология человека. 2015. Т. 41, № 4. С. 82–90. DOI: 10.7868/S0131164615040086

Sharif S., Alway S.Е. The Diagnostic Value of Exercise Stress Testing for Cardiovascular Disease Is More Than Just ST Segment Changes: A Review // J. Integr. Cardiol. 2016. Vol. 2, № 4. P. 341–355. DOI: 10.15761/JIC.1000173

Carlén A., Gustafsson M., Åström Aneq M., Nylander E. Exercise-Induced ST Depression in an Asymptomatic Population Without Coronary Artery Disease // Scand. Cardiovasc. J. 2019. Vol. 53, № 4. P. 206–212. DOI: 10.1080/14017431.2019.1626021

Macfarlane P.W. The Influence of Age and Sex on the Electrocardiogram // Adv. Exp. Med. Biol. 2018. Vol. 1065. P. 93–106. DOI: 10.1007/978-3-319-77932-4_6

Варламова Н.Г., Евдокимов В.Г. Возрастные маркеры ЭКГ // Успехи геронтологии. 2003. Вып. 11. С. 76–79.

Сиротин А.Б., Белозерова Л.М., Щепина Г.М. Влияние двигательной активности на старение мужчин зрелого возраста // Лечеб. физкультура и спорт. медицина. 2009. № 6(66). С. 21–25.

Nakou E.S., Parthenakis F.I., Kallergis E.M., Marketou M.E., Nakos K.S., Vardas P.E. Healthy Aging and Myocardium: A Complicated Process with Various Effects in Cardiac Structure and Physiology // Int. J. Cardiol. 2016. Vol. 209. P. 167–175. DOI: 10.1016/j.ijcard.2016.02.039

Frangogiannis N.G. Cardiac Fibrosis: Cell Biological Mechanisms, Molecular Pathways and Therapeutic Opportunities // Mol. Aspects Med. 2019. Vol. 65. P. 70–99. DOI: 10.1016/j.mam.2018.07.001

Акашева Д.У., Плохова Е.В., Стражеско И.Д., Дудинская Е.Н., Ткачева О.Н. Сердце и возраст (часть II): клинические проявления старения // Кардиоваскуляр. терапия и профилактика. 2013. № 12(4). С. 86–90. DOI: 10.15829/1728-8800-2013-4-86-90

Никитин Ю.П., Хаснулин В.И., Гудков А.Б. Современные проблемы северной медицины и усилия ученых по их решению // Вестн. Сев. (Арктич.) федер. ун-та. Сер.: Мед.-биол. науки. 2014. № 3. С. 63–72.

Hupin D., Edouard P., Oriol M., Laukkanen J., Abraham P., Doutreleau S., Guy J.-M., Carré F., Barthélémy J.-C., Roche F., Chatard J.-C. Exercise Electrocardiogram in Middle-Aged and Older Leisure Time Sportsmen: 100 Exercise Tests Would Be Enough to Identify One Silent Myocardial Ischemia at Risk for Cardiac Event // Int. J. Cardiol. 2018. Vol. 257. P. 16–23. DOI: 10.1016/j.ijcard.2017.10.081

Варламова Н.Г. Артериальное давление у мужчин и женщин Севера // Изв. Коми науч. центра Урал. отдния РАН. 2011. Вып. 4(8). С. 52–55.

Lord R., George K., Somauroo J., Jain N., Reese K., Hoffman M.D., Haddad F., Ashley E., Jones H., Oxborough D. Exploratory Insights from the Right-Sided Electrocardiogram Following Prolonged Endurance Exercise // Eur. J. Sport Sci. 2016. Vol. 16, № 8. P. 1014–1022. DOI: 10.1080/17461391.2016.1165292

La Gerche A., Heidbüchel H., Burns A.T., Mooney D.J., Taylor A.J., Pfluger H.B., Inder W.J., Macisaac A.I., Prior D.L. Disproportionate Exercise Load and Remodeling of the Athlete’s Right Ventricle // Med. Sci. Sports Exerc. 2011. Vol. 43, № 6. P. 974–981. DOI: 10.1249/MSS.0b013e31820607a3

Saltykova M.M. Mechanisms of QRS Voltage Changes on ECG of Healthy Subjects During the Exercise Test // Hum. Physiol. 2015. Vol. 41. P. 62–69. DOI: 10.1134/S0362119714060085

van Lien R., Neijts M., Willemsen G., de Geus E.J.С. Ambulatory Measurement of the ECG T-Wave Amplitude // Psychophysiology. 2015. Vol. 52, № 2. P. 225–237. DOI: 10.1111/psyp.12300

Rutherford J.J., Clutton-Brock T.H., Parkes M.J. Hypocapnia Reduces the T Wave of the Electrocardiogram in Normal Human Subjects // Am. J. Physiol. Regul. Integr. Comp. Physiol. 2005. Vol. 289, № 1. P. R148–R155. DOI: 10.1152/ajpregu.00085.2005

Alexopoulos D., Christodoulou J., Toulgaridis T., Sitafidis G., Manias O., Hahalis G., Vagenakis A.G. Repolarization Abnormalities with Prolonged Hyperventilation in Apparently Healthy Subjects: Incidence, Mechanisms and Affecting Factors // Eur. Heart J. 1996. Vol. 17, № 9. P. 1432–1437. DOI: 10.1093/oxfordjournals.eurheartj.a015079

Евдокимов В.Г., Варламова Н.Г. Возраст и амплитудно-временные характеристики ЭКГ у жителей Севера // Кардиология. 2001. № 2. С. 75.

Vicent L., Martínez-Sellés M. Electrocardiogeriatrics: ECG in Advanced Age // J. Electrocardiol. 2017. Vol. 50, № 5. P. 698–700. DOI: 10.1016/j.jelectrocard.2017.06.003

Rijnbeek P.R., van Herpen G., Bots M.L., Man S., Verweij N., Hofman A., Hillege H., Numans M.E., Swenne C.A., Witteman J.C.M., Kors J.A. Normal Values of the Electrocardiogram for Ages 16–90 Years // J. Electrocardiol. 2014. Vol. 47, № 6. P. 914–921. DOI: 10.1016/j.jelectrocard.2014.07.022

References

Smarż K., Jaxa-Chamiec T., Bednarczyk T., Bednarz B., Eysymontt Z., Gałaszek M., Jegier A., KorzeniowskaKubacka I., Mamcarz A., Mawlichanów A., Piotrowicz R., Rubicki J., Straburzyńska-Migaj E., Szalewska D., Wolszakiewicz J. Electrocardiographic Exercise Testing in Adults: Performance and Interpretation. An Expert Opinion of the Polish Cardiac Society Working Group on Cardiac Rehabilitation and Exercise Physiology. Kardiol. Pol., 2019, vol. 77, no. 3, pp. 399–408. DOI: 10.5603/KP.a2018.0241

Pelliccia A., Sharma S., Gati S., Bäck M., Börjesson M., Caselli S., Collet J.P., Corrado D., Drezner J.A., Halle M., et al. 2020 ESC Guidelines on Sports Cardiology and Exercise in Patients with Cardiovascular Disease. Eur. Heart J., 2021, vol. 42, no. 1, pp. 17–96. DOI: 10.1093/eurheartj/ehaa605

Karpman V.L., Belotserkovskiy Z.B., Gudkov I.A. Issledovanie fizicheskoy rabotosposobnosti u sportsmenov [The Study of Physical Work Capacity in Athletes]. Moscow, 1974. 95 p.

Zav’yalov A.I. Klassifikatsiya izmeneniy elektrokardiogrammy u zdorovogo cheloveka v pokoe i vo vremya fizicheskikh nagruzok [Classification of Electrocardiogram Changes of Healthy Man in Rest and During Physical Activities]. Vestnik Krasnoyarskogo gosudarstvennogo pedagogicheskogo universiteta im. V.P. Astaf’eva, 2013, no. 4, pp. 147–151.

Vanyushin Yu.S., Khayrullin R.R. Kardiorespiratornaya sistema kak indikator funktsional’nogo sostoyaniya organizma sportsmenov [Cardiorespiratory System as an Indicator of Functional State of Athletes]. Teoriya i praktika fizicheskoy kul’tury, 2015, no. 7, pp. 11–14.

Fudin N.A., Klassina S.Y., Pigareva S.N. Relationship Between the Parameters of Muscular and Cardiovascular Systems in Graded Exercise Testing in Subjects Doing Regular Exercises and Sports. Hum. Physiol., 2015, vol. 41, no. 4, pp. 412–419. DOI: 10.1134/S0362119715040088

Sharif S., Alway S.E. The Diagnostic Value of Exercise Stress Testing for Cardiovascular Disease Is More Than Just ST Segment Changes: A Review. J. Integr. Cardiol., 2016, vol. 2, no. 4, pp. 341–355. DOI: 10.15761/JIC.1000173

Carlén A., Gustafsson M., Åström Aneq M., Nylander E. Exercise-Induced ST Depression in an Asymptomatic Population Without Coronary Artery Disease. Scand. Cardiovasc. J., 2019, vol. 53, no. 4, pp. 206–212. DOI: 10.1080/14017431.2019.1626021

Macfarlane P.W. The Influence of Age and Sex on the Electrocardiogram. Adv. Exp. Med. Biol., 2018, vol. 1065, pp. 93–106. DOI: 10.1007/978-3-319-77932-4_6

Varlamova N.G., Evdokimov V.G. Vozrastnye markery EKG [The Ageing Markers of the ECG]. Uspekhi gerontologii, 2003, no. 11, pp. 76–79.

Sirotin A.B., Belozerova L.M., Shchepina G.M. Vliyanie dvigatel’noy aktivnosti na starenie muzhchin zrelogo vozrasta [The Influence of Motional Activity on the Ageing of Males in the Maturity Age]. Lechebnaya fizkul’tura i sportivnaya meditsina, 2009, no. 6, pp. 21–25.

Nakou E.S., Parthenakis F.I., Kallergis E.M., Marketou M.E., Nakos K.S., Vardas P.E. Healthy Aging and Myocardium: A Complicated Process with Various Effects in Cardiac Structure and Physiology. Int. J. Cardiol., 2016, vol. 209, pp. 167–175. DOI: 10.1016/j.ijcard.2016.02.039

Frangogiannis N.G. Cardiac Fibrosis: Cell Biological Mechanisms, Molecular Pathways and Therapeutic Opportunities. Mol. Aspects Med., 2019, vol. 65, pp. 70–99. DOI: 10.1016/j.mam.2018.07.001

Akasheva D.U., Plokhova E.V., Strazhesko I.D., Dudinskaya E.N., Tkacheva O.N. Serdtse i vozrast (chast’ II): klinicheskie proyavleniya stareniya [Heart and Age (Part II): Clinical Manifestations of Ageing]. Kardiovaskulyarnaya terapiya i profilaktika, 2013, vol. 12, no. 4, pp. 86–90. DOI: 10.15829/1728-8800-2013-4-86-90

Nikitin Yu.P., Khasnulin V.I., Gudkov A.B. Sovremennye problemy severnoy meditsiny i usiliya uchenykh po ikh resheniyu [Contemporary Problems of Northern Medicine and Researchers’ Efforts to Solve Them]. Vestnik Severnogo (Arkticheskogo) federal’nogo universiteta. Ser.: Mediko-biologicheskie nauki, 2014, no. 3, pp. 63–72.

Hupin D., Edouard P., Oriol M., Laukkanen J., Abraham P., Doutreleau S., Guy J.-M., Carré F., Barthélémy J.-C., Roche F., Chatard J.-C. Exercise Electrocardiogram in Middle-Aged and Older Leisure Time Sportsmen: 100 Exercise Tests Would Be Enough to Identify One Silent Myocardial Ischemia at Risk for Cardiac Event. Int. J. Cardiol., 2018, vol. 257, pp. 16–23. DOI: 10.1016/j.ijcard.2017.10.081

Varlamova N.G. Arterial’noe davlenie u muzhchin i zhenshchin Severa [Arterial Pressure in Men and Women of the North]. Izvestiya Komi nauchnogo tsentra UrO RAN, 2011, no. 4, pp. 52–55.

Lord R., George K., Somauroo J., Jain N., Reese K., Hoffman M.D., Haddad F., Ashley E., Jones H., Oxborough D. Exploratory Insights from the Right-Sided Electrocardiogram Following Prolonged Endurance Exercise. Eur. J. Sport Sci., 2016, vol. 16, no. 8, pp. 1014–1022. DOI: 10.1080/17461391.2016.1165292

La Gerche A., Heidbüchel H., Burns A.T., Mooney D.J., Taylor A.J., Pfluger H.B., Inder W.J., Macisaac A.I., Prior D.L. Disproportionate Exercise Load and Remodeling of the Athlete’s Right Ventricle. Med. Sci. Sports Exerc., 2011, vol. 43, no. 6, pp. 974–981. DOI: 10.1249/MSS.0b013e31820607a3

Saltykova M.M. Mechanisms of QRS Voltage Changes on ECG of Healthy Subjects During the Exercise Test. Hum. Physiol., 2015, vol. 41, pp. 62–69. DOI: 10.1134/S0362119714060085

van Lien R., Neijts M., Willemsen G., de Geus E.J.C. Ambulatory Measurement of the ECG T-Wave Amplitude. Psychophysiology, 2015, vol. 52, no. 2, pp. 225–237. DOI: 10.1111/psyp.12300

Rutherford J.J., Clutton-Brock T.H., Parkes M.J. Hypocapnia Reduces the T Wave of the Electrocardiogram in Normal Human Subjects. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2005, vol. 289, no. 1, pp. R148–R155. DOI: 10.1152/ajpregu.00085.2005

Alexopoulos D., Christodoulou J., Toulgaridis T., Sitafidis G., Manias O., Hahalis G., Vagenakis A.G. Repolarization Abnormalities with Prolonged Hyperventilation in Apparently Healthy Subjects: Incidence, Mechanisms and Affecting Factors. Eur. Heart J., 1996, vol. 17, no. 9, pp. 1432–1437. DOI: 10.1093/oxfordjournals.eurheartj.a015079

Evdokimov V.G., Varlamova N.G. Vozrast i amplitudno-vremennye kharakteristiki EKG u zhiteley Severa [Age and Amplitude-Temporal Characteristics of ECG in Northerners]. Kardiologiya, 2001, no. 2, p. 75.

Vicent L., Martínez-Sellés M. Electrocardiogeriatrics: ECG in Advanced Age. J. Electrocardiol., 2017, vol. 50, no. 5, pp. 698–700. DOI: 10.1016/j.jelectrocard.2017.06.003

Rijnbeek P.R., van Herpen G., Bots M.L., Man S., Verweij N., Hofman A., Hillege H., Numans M.E., Swenne C.A., Witteman J.C.M., Kors J.A. Normal Values of the Electrocardiogram for Ages 16–90 Years. J. Electrocardiol., 2014, vol. 47, no. 6, pp. 914–921. DOI: 10.1016/j.jelectrocard.2014.07.022

Published

2023-10-09

How to Cite

Kudinova А. ., Varlamova Н. ., & Boyko Е. . (2023). ECG Amplitude Parameters in Men of Different Ages During Submaximal Performance Testing (Exemplified by Residents of the European North of Russia). Journal of Medical and Biological Research, 11(3), 255–264. https://doi.org/10.37482/2687-1491-Z146