The Impact of Viral Infection Caused by SARS-CoV-2 on Fetoplacental Complex Parameters and the Course of Pregnancy in Humans
DOI:
https://doi.org/10.37482/2687-1491-Z289Keywords:
pregnancy, rats, COVID-19 infection, preeclampsia, Doppler ultrasound, cardiotocographyAbstract
To assess the impact of COVID-19 infection in late pregnancy on fetoplacental complex parameters and the course of pregnancy, a retrospective analysis of medical records of patients registered at Simferopol Clinical Maternity Hospital No. 2, who were infected with SARS-CoV-2 in the second and third trimesters, was conducted. A trimester-dependent impact of COVID-19 infection on pregnancy has been established. In the second trimester, COVID-19 is associated with a more severe course of the disease in mothers and causes significant disturbances in the uteroplacental circulation system, the development of placental dysfunction (according to Doppler ultrasound data), and abnormal cardiotocogram changes in the fetus (decreased heart rate variability and late decelerations). Infection in the third trimester is more closely associated with the development of obstetric complications, while placental dysfunction is less pronounced than in those infected in the second trimester. For this category of patients, it is advisable to implement personal monitoring protocols with the expanded use of Doppler ultrasound and cardiotocography in order to promptly identify preclinical disorders.
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Copyright (c) 2026 Nikitina K.A., Gafiyatullina G.Sh., Zyablitskaya E.Yu., Marulova A.V.
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